Partamol C

OTC

Indications:

For treatment of illness with pain or fever, such as headaches, influenza-like conditions, dental pain, muscular pain, menstrual period pain, in adult and in children weighing more than 25 kg (about 8 years of age).

Dosage:

Adults, children over 50 kg (about 15 years of age): 1 – 2 effervescent tablets. Doses may be repeated up to every 4 hours, maximum 9 tablets daily.

Children:

• Children 25 – 30 kg (about 8 – 10 years of age): 1 effervescent tablet. Doses may be repeated up to every 6 hours, maximum 5 tablets daily.
• Children 30 – 35 kg (about 10 – 12 years of age): 1 – 2 effervescent tablets. Doses may be repeated up to every 6 hours, maximum 6 tablets daily.
• Children 35 – 50 kg (about 12 – 15 years of age): 1 – 2 effervescent tablets. Doses may be repeated up to every 6 hours, maximum 7 tablets daily.

Usage:

Partamol C is administered orally. The effervescent tablet is dissolved in a glass of water.

Hypersensitivity to any of the ingredients.

Large dose of vitamin C should be avoid in patients with:

• Glucose – 6 – phosphate dehydrogenase deficiency (risk of hemolytic anemia).
• History of nephrolithiasis, hyperoxaluria (increased risk of renal stone formation).
• Thalassemia (increased risk of iron absorption).

Thrombocytopenia, leucopenia, pancytopenia, neutropenia and agranulocytosis; nephropathy when abuse or prolonged excessive use of paracetamol; asthma; angioedema, eruptions.

Hyperoxaluria, nausea, vomiting, heartburn, abdominal cramps, fatigue, flushing, headache, insomnia and sleepiness have been reported, diarrhoea.

Paracetamol should be given with care to patients with impaired kidney or liver function. It should also be given with care to patient with alcohol dependence.

Prolonged use of large doses of vitamin C may result in increased metabolism of the drug, scurvy may occur when intake of the vitamin is reduced to normal. Ingestion of large doses of the vitamin C during pregnancy has results in scurvy in neonates.

Hemolysis has been associated with vitamin C administration in neonates with glucose-6-phosphate dehydrogenase deficiency and in otherwise healthy premature neonates.

The physicians need to warn the patients of the signs of serious skin reactions known as Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) or Lyell’s syndrome, acute generalized exanthematous pustulosis (AGEP).

Partamol C contains aspartame. Aspartame is a source of phenylalanine. It may be harmful if you have phenylketonuria (PKU), a rare genetic disorder in which phenylalanine builds up because the body cannot remove it properly.

Partamol C contains anhydrous sodium bicarbonate, anhydrous sodium carbonate, sodium benzoate, sodium saccharin; therefore, patients should have dietary sodium restriction.

Partamol C contains tartrazine dye, which may cause allergic reactions.

Paracetamol infrequent should remain the analgesic of choice in pregnancy. Use with caution in nursing women.

Patients should be aware of how they react to drug before driving or operating machinery.