Partamol 150

OTC

Indications:

For treatment of mild to moderate pain and fever, especially in patients in whom salicylates are contraindicated or not tolerated. The drug is most effective in relieving low intensity pain of non-visceral origin.

Dosage:

Paracetamol should not be used for self-medication of pain for longer than 5 days in children.

Paracetamol should not be used for self-medication of marked fever (greater than 39.5^oC), fever persisting longer than 3 days, or recurrent fever.

Paracetamol should not be used in children for self-medication of sore throat pain (pharyngitis, laryngitis, tonsillitis) for longer 2 days.

Children may receive is 10 – 15 mg/kg per dose with a maximum of 5 doses per day or the following doses every 4 – 6 hours as necessary (up to 5 times in 24 hours) with normally dosages:

• Children 11 years of age (weighing 32.5 – 43 kg): 480 mg (about 3 sachets), repeated if necessary after interval of 4 hours, without exceeding 12 sachets per day.
• Children 9 – 10 years of age (weighing 27 – 32.5 kg kg): 400 mg (about 2.5 sachets), repeated if necessary after interval of 6 hours, without exceeding 12 sachets per day.
• Children 6 – 8 years of age (weighing 21.5 – 27 kg): 320 mg (about 2 sachets), repeated if necessary after interval of 4 hours, without exceeding 8 sachets per day.
• Children 4 – 5 years of age (weighing 16 – 21.5 kg): 240 mg (about 1.5 sachets), repeated if necessary after interval of 6 hours, without exceeding 8 sachets per day.
• Children 2 – 3 years of age (weighing 11 – 16 kg): 160 mg (about 1 sachets), repeated if necessary after interval of 4 hours, without exceeding 6 sachets per day.
• Children 12 -23 months of age (weighing 8 – 11 kg): 120 mg (about 1 sachets), repeated if necessary after interval of 6 hours, without exceeding 4 sachets per day.

Usage:

Partamol 150 is administered orally. The effervescent granules must be dissolved in water and the solution should then be drunk after complete dissolution of the granules.

Patients with anemia or cardiac, pulmonary, renal, or hepatic disease.

Patients with alcohol dependence.

Patients with known hypersensitivity to paracetamol or any of the excipients listed in.

Patients with known glucose – 6 – phosphate dehydrogenase deficiency.

Uncommon: Rash, nausea, vomiting, blood dyscrasias (neutropenia, pancytopenia, leukopenia), anemia, nephropathy, nephrotoxicity with chronic abuse.

Paracetamol should be used with caution in patients with preexisting anemia, since cyanosis may not be apparent despite dangerously high blood concentrations of methemoglobin.

Excessive intake of alcohol may increase the risk of paracetamol induced hepatotoxicity; avoid or limit alcohol intake.

Caution is recommended when giving to patients with hepatic or renal impairment, susceptible individuals.

The physicians need to warn the patients of the signs of serious skin reactions known as Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) or Lyell’s syndrome, acute generalized exanthematous pustulosis (AGEP).

Partamol 150 contains aspartame. Aspartame is a source of phenylalanine. It may be harmful if you have phenylketonuria (PKU), a rare genetic disorder in which phenylalanine builds up because the body cannot remove it properly.

Partamol 150 contains saccharose (sucrose). Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency should not take this medicine.

Infrequent paracetamol should remain the analgesic of choice in pregnancy. Caution when use paracetamol for breastfeeding women.

Patients should be aware of how they react to Partamol 150 before driving or operating machinery.