Misoprostol STELLA 200 mcg

Rx

Indications:

• Reducing the risk of nonsteroidal anti-inflammatory agent-induced gastric ulcer.
• Short-term treatment of active duodenal ulcer and active benign gastric ulcer.
• Maintenance therapy following healing of gastric ulcer to reduce ulcer recurrence.
• Adjunct to mifepristone for the medical termination of intrauterine pregnancy according to the “National Guideline on reproductive health care services” issued together with the Minister of Health’s Decision No. 4128 / QD-BYT dated July 29, 2016.

Dosage:

Adults:

• Prevention of NSAID-induced ulcers: 200 mcg 4 times daily, reduce doses to 100 mcg 4 times daily in patients who do not tolerate the usual dosage.
• Gastric ulcer: 100 – 200 mcg 4 times daily for 8 weeks.
• Duodenal ulcer: 100 – 200 mcg 4 times daily or 400 mcg twice daily for 4 – 8 weeks.
• Support mifepristone in abortion: In accordance with “National Guideline on reproductive health care services” issued together with Decision No. 4128 / QD-BYT dated July 29, 2016 of the Minister of Health.

Usage:

Misoprostol STELLA  200 mcg is administered orally. The incidence of misoprostol induced diarrhea may be minimized by using in divided doses after meals and at bedtime and by avoiding concomitantly use with a magnesium-containing or other laxative antacid.

Pregnant women and women planning a pregnancy.

Allergic to misoprostol or other prostaglandins or any component of the drug.

For indications for mifepristone support during pregnancy termination:

• Absolute contraindications:
• Mitral valve stenosis, embolism and history of embolism.
• Adrenal gland disease.
• Blood coagulation disorders, using anticoagulants.
• Anemia (severe and moderate).
• Confirmed or suspected ectopic pregnancy.
• Pregnant at the old surgical wound in the uterus.
• Vegetable with comb teeth.

Relative contraindications:

• Long-term treatment with systemic steroids.
• Are acute genital tract infections.
• Genital deformities.
• Scarring of uterus with caution.

Diarrhoea; abdominal pain, dyspepsia, flatulence, nausea and vomiting; uterine contractility, abnormal vaginal bleeding (menorrhagia and intermenstrual bleeding); skin rash, headache, dizziness; hypotension rarely occurs.

• Caution in patients with pre-existing cardiovascular disease, enteritis, patients prone to dehydration.
• Self-use of abortion pills can be life-threatening, please follow the instructions of the treating physician and National guidelines on reproductive health care services specified in Decision No. 4128/QD-BYT dated July 29, 2016 of the Minister of Health.
• Misoprostol should not be used by nursing women.
• Patients should be cautious when driving or operating machinery because misoprostol may cause dizziness.