Spirastad 1.5 M.I.U

Spirastad 1.5 M.I.U contains spiramycin is considered as a second-line drug for treatment of infectious conditions in respiratory, cutaneous and genital tracts caused by sensitive organisms.

Pack size Box of 10 tablets, 30 tablets, 100 tablets
Shelf-life 24 months
Composition Spiramycin
Dosage forms and strengths Film-coated tablet: 1,500,000 IU (1.5 million IU)
Product code :



  • Infectious conditions in respiratory, cutaneous and genital tracts caused by sensitive organisms.
  • Prophylaxis of meningitis caused by Meningococci in patients with contraindication to rifampicin.
  • Prevention of congenital toxoplasmosis during pregnancy.
  • Chemoprophylaxis of recurrent acute rheumatic arthritis in patients allergic to penicillins.


  • Adults: 5 million – 3 million IU, 3 times daily.
  • Infants and children: 150 thousand IU/kg daily, in 3 divided doses.

Prophylaxis of meningitis due to Meningococci

  • Adults: 3 million IU every 12 hours.
  • Children: 75 thousand IU/kg every 12 hours for 5 days.

Prevention of congenital toxoplasmosis during pregnancy

  • 9 million IU daily in divided doses for 3 weeks, repeated 2-weekly intervals.
  • Combination or alternation with a pyrimethamine/sulfonamide regimen may improve results.


  • Spirastad 1.5 M.I.U is administered orally. Because food in the stomach reduces the bioavailability of spiramycin, the dose should be administered at least 2 hours before or 3 hours after a meal.
  • Patients taking spiramycin should comply with the full course of therapy.

Patients with known hypersensitivity to spiramycin, erythromycin or to any ingredient in the formulation.


  • Nausea, vomiting, diarrhea, indigestion.


  • Fatigue, epistaxis, sweating, heaviness in the chest, transient paresthesias, dysesthesia, giddiness, pain, muscular and knuckle stiffness;
  • Acute colitis;
  • Rash, exanthema, urticaria.
  • Spiramycin should be used cautiously in patients with hepatic dysfunction;
  • Pregnant women.
  • Mothers should discontinue breast feeding during spiramycin administration.