Infectious conditions in respiratory, cutaneous and genital tracts caused by sensitive organisms.
Prophylaxis of meningitis caused by Meningococci in patients with contraindication to rifampicin.
Prevention of congenital toxoplasmosis during pregnancy.
Chemoprophylaxis of recurrent acute rheumatic arthritis in patients allergic to penicillins.
Treatment of infectious conditions in respiratory, cutaneous and genital tracts; Chemoprophylaxis of recurrent acute rheumatic arthritis in patients allergic to penicillins:
- Adults: 5 million – 3 million IU daily, in 2 or 3 divided doses. Doses up to 15 million units have been given daily in divided doses for severe infections.
- Children ≥ 30 kg: 150 thousand IU/kg daily, in 3 divided doses. Use other preparation for children < 30 kg.
Prophylaxis of meningitis due to Meningococci:
- Adults: 3 million IU every 12 hours for 5 days.
- Children ≥ 20 kg: 75 thousand IU/kg every 12 hours for 5 days. Use other preparation for children < 20 kg.
Prevention of congenital toxoplasmosis during pregnancy: 9 million IU daily in divided doses for 3 weeks, repeated 2-weekly intervals
Spirastad 3 M.I.U is administered orally. Because food in the stomach reduces the bioavailability of spiramycin, the dose should be administered at least 2 hours before or 3 hours after a meal.