Pracetam 400

Piracetam is a psychotropic agent which acts directly on the brain to improve the efficacy of the telencephalon in both normal subjects and those suffering from some functional deficit, heighten alertness and increase cognitive function.

Pack size Box of 60 tablets, 100 tablets
Shelf-life 36 months
Composition Piracetam
Dosage forms and strengths Film-coated tablet: 400 mg
Product code :



  • Vertigo
  • Elderly suffering from memory impairment, vertigo, a lack of concentration or of alertness, changes of mood, a deterioration in behaviour and personal negligence, the dementia produced by multiple cerebral infarcts.
  • Chronic alcoholism.
  • Sickle-cell anemia.
  • Myoclonus of cortical origin.


  • The total daily dose:
    30 – 160 mg/kg/day. This is administered twice daily, but may also be given in 3 or 4 separate doses.
  • As a long-term therapy for psycho-organic syndrome in the elderly:
    2 – 2.4 g daily. The loading dose can be as high as 4.8 g/day during the initial weeks of treatment.
  • Sickle-cell anemia:
    160 mg/kg/day divided in 4 equal doses.
  • Alcoholism:
    12 g daily during the initial withdrawal period.
    Subsequent maintenance therapy: Oral daily dose of 2.4 g.
  • Cognitive deficits resulting from head injury, whether or not these are associated with vertigo:
    Initial dose can vary from 9 – 12 g daily. Maintenance therapy thereafter is a daily oral dose of 2.4 g, given for a period of not less than 3 weeks.
  • In cortical myoclonus:
    Doses of 7.2 g are given daily increasing by 4.8 g daily every 3 or 4 days up to a maximum of 20 g daily. It is given in 2 or 3 divided doses. Attempts should be made to reduce the dose of other drugs.
  • Children under 16 years are not recommended.
  • Renal impairment: Dosage should be reduced:
    CC between 50 and 79 ml/minute: 2/3 of the usual dose, given in 2 or 3 divided doses.
    CC between 30 and 49 ml/minute: 1/3 of the usual dose, given in 2 divided doses.
    CC between 20 and 29 ml/minute: 1/6 of the usual dose, given as a single dose.
    CC less than 20 ml/minute: Contraindicated.


  • Pracetam 400 is administered orally.
  • Hypersensitivity to piracetam, other pyrrolidone derivatives or any of the excipients.
  • Severe renal insufficiency, as demonstrated by a creatinine clearance of < 20 ml/min.
  • Patients with cerebral haemorrhage, suffering from Huntington’s Chorea.


  • Fatigue,
  • Nausea, vomiting, diarrhea, stomachache,
  • Nervousness, irritability, headache, insomnia and somnolence.
  • Special care must be taken when treating patients known to suffer from renal insufficiency, the older patient. Monitoring of renal function is recommended in such cases.
  • Caution in patients with: renal insufficiency; severe haemorrhage; at risk of bleeding; underlying disorders of haemostasis; history of haemorrhagic CVA; undergoing major surgery; using anticoagulants or platelet antiaggregant drugs.
  • Abrupt discontinuation of treatment should be avoided in myoclonic patients.
  • Pracetam 400 should not be used during pregnancy and during breastfeeding or breastfeeding should be discontinued, while receiving treatment with piracetam.
  • Caution should therefore be exercised by patients intending to drive or use machinery whilst taking Pracetam 400.