Elderly suffering from loss of memory, vertigo, a lack of concentration or of alertness, changes of mood, a deterioration in behaviour and personal negligence, the dementia produced by multiple cerebral infarcts.
Treatment of vertigo.
Treatment for chronic alcoholism.
Adjunctive treatment of myoclonus of cortical origin.
As a long-term therapy for psycho-organic syndrome in the elderly: Doses ranging from 1.2 – 2.4 g daily. The loading dose can be as high as 4.8 g daily during the initial weeks of treatment.
Cognitive deficits resulting from head injury, whether or not these are associated with vertigo: The initial dose can vary from 9 – 12 g daily. Maintenance therapy thereafter: 2.4 g daily for 3 weeks at least.
Sickle-cell anemia: 160 mg/kg/day divided in 4 equal doses.
Alcoholism: 12 g daily during the initial withdrawal period. Subsequent maintenance therapy: 2.4 g daily
Cortical myoclonus: 7.2 g daily increasing by 4.8 g daily every 3 or 4 days up to a maximum of 20 g daily given in 2 or 3 divided doses.
Administration in renal impairment:
- CC between 50 and 79 ml/minute: Two-thirds of the usual dose, given in 2 or 3 divided doses;
- CC between 30 and 49 ml/minute: One-third of the usual dose, given in 2 divided doses;
- CC between 20 and 29 ml/minute: One-sixth of the usual dose, given as a single dose;
- CC less than 20 ml/minute: Contraindicated.
Pracetam 400 CAP is orally administered. This is administered twice daily, but may also be given in 3 or 4 separated doses.