Stadsone 16

Rx

Indications:

An anti-inflammatory or immunosuppressive treatment for some diseases including causes due to hematology, allergies, arthritis, cancer and autoimmune.

Dosage:

• Adult: initial dosage from 2 – 60 mg daily in 4 divided doses.
• Children: based on the severity of the disease and the response, after a satisfactory response is obtained, dosage should be decreased in small decrements to the lowest level that maintains adequate clinical response.
• When long-term use: consider an alternate day dosage regimen, then withdrawn gradually.
• Contact dermatitis: 24 mg (6 tablets of 4 mg) for the first day, then tapered by 4 mg daily until 21 tablets have been administered for 6 days.
• Asthma:
  • Children < 4 years old (more than 3 exacerbations per year) and children 5 – 11 years old (at least 2 exacerbations per year): 1 – 2 mg/kg/day (maximum 60 mg daily) may be added to existing asthma therapy.
  • Adults and adolescents (at least 2 exacerbations per year): 40-60 mg daily as a single dose or in 2 divided doses, may be added to low-to-high maintenance dosages in the inhaled corticosteroid and a long-acting inhaled b₂-agonist bronchodilator, a short course (usually 3 – 10 days) of oral corticosteroid therapy should be continued until the patient achieves a peak expiratory flow (PEF) of 80% of his or her personal best and until symptoms resolve. Once asthma is well controlled, repeated attempts should be made to reduce the oral corticosteroid dosage.

Usage:

Oral administration.

• Known hypersensitivity to any of the active substance or excipients.
• Serious infections, except septic shock and tuberculous meningitis.
• Viral, fungal, or tubercular skin lesions.
• Administration of live virus vaccines.

Most commonly when using methylprednisolone in high doses and long-term therapy: insomnia, nervousness; increased appetite, indigestion; hirsutism; diabetes mellitus; arthralgia; cataracts, glaucoma; epistaxis.

• Patients with osteoporosis, newly established anastomoses, psychosis, gastric ulcer, duodenal ulcer, diabetes, hypertension, cardiac insufficiency and growing individuals (children), hepatic failure, renal failure, glaucoma, thyroid disease, cataracts.
• Elderly (Stadsone 16 should be used cautiously with the smallest possible dose, and for the shortest possible time).
• The use of Stadsone 16 in pregnant women requires that the anticipated benefits of the drug should be weighed against possible hazards to the mother and the child.
• Acute adrenal insufficiency may occur with abrupt withdrawal after long-term therapy or with stress.
• High doses can interference with vaccination.