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Predstad 20
Rx

Prednisone is a synthetic adrenocortical steroid with the principal characteristics of a glucocorticoid.

Pack size Box of 20 tablets
Shelf-life 24 months
Composition Prednisolone
Dosage forms and strengths Water-dispersible tablet: 20 mg
Product code :

PRESCRIBING INFORMATION

Indications:

Treatment and/or suppression of inflammatory and allergic disorders.

Dosage:

  • The lowest effective dose should be used for the minimum period.
  • Adults and the elderly: initial 5 – 60 mg daily or more, divided into doses; initial dosage shall be maintained or adjusted until the anticipated response; the dose should be gradually reduced until the lowest dose which will maintain an adequate clinical response.
    • Prolonged therapy: dosage may need to be temporarily increased during periods of stress or during exacerbations of the disease. If there is lack of a satisfactory clinical response: gradually discontinue drug and transfer to alternative therapy.
    • Intermittent dosage regimen: A single dose in the morning on alternate days or at longer intervals.
  • Some corticosteroid responsive disorders: Acute/severe disease: may require initial high dose therapy with reduction to the lowest effective maintenance dose as soon as possible. Dosage reductions should not exceed 5 – 7.5 mg daily during chronic treatment.
  • Allergic and skin disorders: Initial doses are 5 – 15 mg daily.
  • Collagenosis: initial doses are 20 – 30 mg daily, more severe symptoms may require higher doses.
  • Rheumatoid arthritis: an initial dose is 10 – 15 mg daily, the lowest daily maintenance dose compatible with tolerable symptomatic relief is recommended.
  • Blood disorders and lymphoma: an initial daily dose is 15 – 60 mg, dosage reduction after an adequate clinical or haematological response. Higher doses may be necessary to induce remission in acute leukaemia.
  • Children: only prescribed on special indicated, dosage will usually be determined by clinical response as in adults. Alternate day dosage is preferable where possible.

Usage:

Predstad 20 is orally administered by dispersing in a little water. The daily dose should be taken in the morning after breakfast.

  • Known hypersensitivity to any of the active substance or excipients.
  • Serious infections, except septic shock and tuberculous meningitis.
  • Viral, fungal, or tubercular skin lesions.
  • Administration of live virus vaccines.

Irritable, euphoric, depressed and labile mood, and suicidal thoughts, psychotic reactions, mania, delusions, hallucinations, and aggravation of schizophrenia; behavioural disturbances, irritability, anxiety, sleep disturbances, and cognitive dysfunction including confusion and amnesia.

  • Patients or their first degree relatives with existing or previous history of severe affective disorders.
  • Diabetes mellitus/glaucoma or in those with a family history of diabetes/ glaucoma; hypertension; congestive heart failure; liver failure; epilepsy; osteoporosis; previous history of corticosteroid induced psychoses; peptic ulceration; previous steroid myopathy; myasthenia gravis receiving anticholinesterase therapy; thromboembolic disorders; renal insufficiency; history of, or x-ray changes characteristic of tuberculosis; recent myocardial infarction (rupture); chickenpox; measles; hypothyroidism in those with chronic liver disease with impaired hepatic function.
  • Elderly: Adrenal cortical atrophy develops during prolonged therapy and may persist for years after stopping treatment.
  • Corticosteroids cause growth retardation in infancy, childhood and adolescence, which may be irreversible.
  • Potentially severe psychiatric adverse reactions may occur with systemic steroids.
  • Too rapid a reduction of corticosteroid dosage following prolonged treatment can lead to acute adrenal insufficiency, hypotension and death.
  • Pregnancy: only be prescribed when the benefits to the mother and child outweigh the risks.