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Acyclovir STELLA 800 mg
Rx

Acyclovir is a synthetic purine nucleoside analogue with in vitro and in vivo inhibitory activity against Herpes simplex virus types 1 (HSV-1), 2 (HSV-2) and Varicella zoster virus (VZV).

Pack size Box of 35 tablets, 50 tablets
Shelf-life 48 months
Composition Acyclovir
Dosage forms and strengths Tablet: 800 mg
Product code :

PRESCRIBING INFORMATION

Indications:

  • Treatment for Herpes simplex virus infections of the skin and mucous membranes including initial and recurrent genital herpes, Varicella (chickenpox) and Herpes zoster (shingles).
  • Suppression of recurrent Herpes simplex infections in immunocompetent patients.
  • Prophylaxis of Herpes simplex infections in immunocompromised patients.

Dosage:

  • Primary Herpes simplex infections, including genital herpes: 200 mg five times daily (usually every 4 hours while awake) for 5 – 10 days. Severely immunocompromised patients or those with impaired absorption: 400 mg five times daily for 5 days. Renal impairment (CC < 10 ml/minute): 200 mg every 12 hours.
  • Suppression of recurrent Herpes simplex in immunocompetent patients: 800 mg daily in 2 – 4 divided doses (reduction to 400 – 600 mg daily can be tried, dosage > 1 g daily have also been used. Interrupt every 6 – 12 months for reassessment.
  • Prophylaxis of Herpes simplex in immunocompromised patients: 200 to 400 mg four times daily. Children < 2 years old: Half the adult dose.
  • Chronic suppressive treatment: 200 mg five times daily for 5 days, preferably initiated during the prodromal period.
  • Chickenpox: 800 mg four or five times daily for 5 to 7 days. Renal impairment CC < 10 ml/minute: 800 mg every 12 hours; CC 10 – 25 ml/minute: 800 mg three times daily every 8 hours.
  • Herpes zoster: 800 mg five times daily may be given for 7 to 10 days.

Use of Acyclovir STELLA 200 mg and/ or Acyclovir STELLA 400 mg is recommended when using doses of 200 mg, 400 mg.

Usage:

Acyclovir STELLA 800 mg is orally taken.

Patients who develop hypersensitivity to acyclovir or valacyclovir.

  • Renal impairment is usually reversible and may progress to acute renal failure.
  • Increased serum bilirubin and liver enzymes, haematological changes, skin rashes (including erythema multiform, Stevens-Johnson syndrome and toxic epidermal necrolysis), fever, headache, dizziness; nausea, vomiting and diarrhoea. Anaphylaxis. Hepatitis and jaundice have been reported rarely.
  • Elderly patients and patients with renal impairment are at increased risk of developing neurological side effects and should be closely monitored.
  • Pregnancy (only if the potential benefit justifies the potential risk). Nursing mother (only when indicated).