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Acyclovir STELLA 200 mg
Rx

Acyclovir is a synthetic purine nucleoside analogue with in vitro and in vivo inhibitory activity against Herpes simplex virus types 1 (HSV-1), 2 (HSV-2) and Varicella zoster virus (VZV).

Pack size Box of 25 tablets, 50 tablets
Shelf-life 48 months
Composition Acyclovir
Dosage forms and strengths Tablet: 200 mg
Product code :

PRESCRIBING INFORMATION

Inidcations:

Treatment of Herpes simplex virus (HSV) infections

  • Treatment of initial and recurrent HSV infection (type 1 and 2) in mucosa – skin (stomatitis, genital inflammation), in eye (keratitis).
  • Prophylaxis of HSV infection in mucosa – skin when recurrences occur at least 6 times a year, in eyes (recurrent keratitis occur after twice a year) or in eye surgery.

Treatment of Varicella zoster virus infection (VZV)

  • Herpes zoster, prophylaxis of complications in eye due to zoster in eye.
  • Chickenpox in patients more than 2 years of age.

Dosage:

  • Primary HSV infections, including genital herpes: 200 mg five times daily every 4 hours for 5 – 10 days. Severely immunocompromised patients or those with impaired absorption: 400 mg five times daily for 5 days
  • Suppression of recurrent HSV in immunocompetent patients (³ 6 times/year): 800 mg daily in 2 or 4 divided doses. Reassessment should be performed after 6 – 12 months of treatment.
  • Prophylaxis of HSV in immunocompromised patients: 200 to 400 mg four times daily.
  • HSV infection in eyes: Keratitis: 400 mg x 5 times/day in 10 days. Prophylaxis of recurrence of keratitis (after 3 recurrences a year): 800 mg/day in 2 divided doses. Reassessment should be performed after 6 – 12 months of treatment. Eye surgery: 800 mg/day in 2 divided doses.
  • Herpes zoster: Adults and children > 2 years: 800 mg five times daily may be given for 5 to 10 days.
  • Chickenpox: Adults: 800 mg four or five times daily for 5 to 7 days. Children > 2 years: 20 mg/kg, not more than 800 mg four times daily for 5 days. Children from 2 to 5 years: 400 mg four times daily. Children ≥ 6 years: 800 mg four times daily.
  • Renal impairment associated with HIV experienced hemodialysis: 200 – 800 mg every 6 – 8 hours (ClCr 50 – 80 ml/min), every 8 – 12 hours (ClCr 25 – 50 mL/min), every 12 – 24 hours (ClCr 10 – 25 mL/min); 200 – 400 mg every 24 hours (ClCr < 10 mL/min); add 1 dose immediately after hemodialysis.

Usage:

Acyclovir STELLA 200 mg is orally taken.

 

Patients who develop hypersensitivity to acyclovir or valacyclovir.

Common: Dizziness and headache. Nausea, vomiting, diarrhoea and abdominal pain. Skin rashes, pruritus (including photosensitivity). Fatigue, fever.

  • Elderly patients and patients with renal impairment are at increased risk of developing neurological side effects and should be closely monitored.
  • Pregnancy (only if the potential benefit justifies the potential risk). Nursing mother (only when indicated).
  • Patients should be aware of how they react to drug before driving or operating machinery.