Diltiazem STELLA 60 mg

Rx

Indications:

Prophylaxis and treatment of angina pectoris.

Dosage:

• Adults: The usual dose is 1 tablet three times daily. If necessary the divided dose may be increased to 6 tablets daily. Higher doses up to 8 tablets daily have been used with benefit in some patients especially in unstable angina.
• Elderly and patients with impaired hepatic or renal function: The starting dose is one tablet twice daily. The dose should not be increased if the heart rate falls below 50 beats per minute.
• Diltiazem is not recommended for use in children.

Usage:

Diltiazem STELLA 60 mg is administered orally. It should be taken with a glass of water before meals, swallowed the whole tablet, should not be chewed, broken, crushed.

• Known hypersensitivity to any of the active substance or excipients.
• Sinus dysfunction.
• 2^nd and 3^rd degree atrioventricular block.
• Left ventricular failure with pulmonary stasis.
• Severe bradycardia (less than 50 beats per minute)
• Lactation.
• Concurrent use with dantrolene infusion
• Combination with ivabradine
• Patients with severe hypotension (less than 90 mmHg systolic)
• Patients with acute myocardial infarction and pulmonary congestion documented by x-ray on admission.

• Peripheral oedema.
• Headache, dizziness.
• Atrioventricular block, palpitations.
• Flushing.
• Constipation, dyspepsia, gastric pain, nausea.
• Erythema, Malaise.

• Use with caution in patients with reduced left ventricular function, bradycardia or with a 1^st degree AV block or prolonged PR interval detected on the electrocardiogram; in patients at risk of developing an intestinal obstruction; patients with latent or manifest due to a possible increase in blood glucose.
• Drug discontinuation should be considered if mood changes, including depression.
• Diltiazem is not recommended during pregnancy, as well as in women of child-bearing potential not using effective contraception. Breastfeeding is not recommended during drug administration.
• Patients should be aware of how they react to drug before driving or operating machinery.