BK-2

OTC

Indications:

For emergency contraceptive, BK-2 is taken within 72 hours of unprotected intercourse, or failure of contraceptive method.

Dosage:

• One tablet is taken within 72 hours of unprotected intercourse (as soon as possible), and repeated 12 hours later.
• If vomiting occurs within 3 hours after intaking the drug, additional administration should be started immediately.
• BK-2 is administered at any time during the menstrual cycle, but not at a delayed menses.
• Take a double dose of levonorgestrel (i.e. 3000 microgram within 72 hours after the unprotected intercourse) for those women unable or unwilling to use Cu-IUD.

Usage:

BK-2 is orally administered.

• Hypersensitivity to levonorgestrel or to any of the components of the drug.
• Severe hepatic impairment; Undiagnosed abnormal vaginal bleeding; Active thrombophlebitis or thromboembolic disorders; Acute liver disease, benign or malignant liver tumors; A history of breast cancer; Jaundice or persistent itching during a previous pregnancy; Disorders of acute porphyria; History of increased idiopathic intracranial pressure.
• Known or suspected pregnancy.

Very common:

• Headache, nausea, abdominal pain lower, bleeding not related to menses, fatigue.

Common:

• Dizziness, diarrhoea, vomiting, delay of menses more than 7 days (if the next menstrual period is more than 5 days overdue, pregnancy should be excluded); menstruation irregular, breast tenderness.

• After emergency contraceptive intaking, an additional method of contraception, e.g. sheath (as condom) is applied until the next cycle.
• BK-2 is not contraindicated in combination with other oral hormonal contraceptives.
• BK-2 is not recommended using for children, severe hepatic impairment.
• Emergency contraception is an inactive method of contraception, only applied in “emergencies”.
• Emergency contraceptives fail in preventing pregnancy in any situation. Intaking BK-2 after the second intercourse may be ineffective.
• If pregnancy comes after intaking BK-2, the risk of extrauterine pregnancy should be considered, mostly in patients experiences abdominal pain/ pain in pelvic or depression, patients with a history of extrauterine pregnancy, tubal surgery, pelvic inflammatory disease.
• With BK-2, natural cycle of menses control is good after initial intaking, some women may experience early or delayed onset of menses. Physicians should advise patients applying some frequent normal methods of contraception.
• Administering BK-2 with repeated dose in one menstruation cycle is not advised, due to the possibility of oligomenorrhea.
• BK-2 does not show an as good contraceptive efficiency as other frequent conventional contraceptives, and only used for emergency circumstances. Emergency method of contraception is not a substitution of other precautious method to prevent sexual transmitted diseases.
• BK-2 contains lactose. Patients with rare hereditary problems of galactose intolerance, total lactase deficiency or glucose-galactose malabsorption should not take this medicine.
• BK-2 should not be given to pregnant women.
• The breast-feeding woman takes the tablet immediately after feeding and avoids nursing at least 8 hours following levonorgestrel administration.
• BK-2 increases the possibility of cycle disturbances.
• Patients should be aware of how they react to drug before driving or operating machinery.