Trimetazidine STELLA 20 mg

In patients with ischaemic heart disease, trimetazidine acts as a metabolic agent, preserving the myocardial high-energy phosphate intracellular levels. Anti-ischemic effects are achieved without concomitant haemodynamic effects.

Pack size Box of 60 tablets
Shelf-life 36 months
Composition Trimetazidine dihydrochloride
Dosage forms and strengths Film coated tablet: 20 mg
Product code :



  • Trimetazidine is indicated in adults as add-on therapy for the symptomatic treatment of patients with stable angina pectoris who are inadequately controlled by or intolerant to first-line antianginal therapies.


  • Usual dose:
    One tablet, three times a day during meals.
  • Elderly, patients with moderate renal impairment (creatinine clearance [30- 60] ml/min):
    The recommended dose is one tablet, twice daily, one in the morning and one in the evening during meals.
  • Children:
    The safety and efficacy of trimetazidine in children aged below 18 years have not been established.


  • Administered orally at meal times.
  • Hypersensitivity to any of the ingredients.
  • Parkinson disease, parkinsonian symptoms, tremors, restless leg syndrome, and other related movement disorders.
  • Severe renal impairment (creatinine clearance < 30 ml/min).
  • Dizziness, headache.
  • Abdominal pain, diarrhoea, dyspepsia, nausea and vomiting.
  • Rash, pruritus, urticaria.
  • Asthenia.
  • In the absence of clinical data and for safety reasons, trimetazidine should not be prescribed to pregnancy and nursing women.
  • Trimetazidine can cause or worsen parkinsonian symptoms (tremor, akinesia, hypertonia), which should be regularly investigated, especially in elderly patients.
  • The occurrence of movement disorders such as parkinsonian symptoms, restless leg syndrome, tremors, gait instability should lead to definitive withdrawal of trimetazidine.
  • Falls may occur, related to gait instability or hypotension, in particular in patients taking antihypertensive treatment.
  • Caution should be exercised when use for patients with moderate renal impairment, elderly patients older than 75 years old.
  • Trimetazidine may cause symptoms, such as dizziness and drowsiness which may affect ability to drive and use machines. Patients should be aware of how they react to drug before driving or operating machinery.