Stadovas 10 Tab

Rx

Indications:

Hypertension. Chronic stable angina pectoris. Vasospastic (Prinzmetal’s) angina.

Dosage:

• Adults: For both hypertension (in combination with a thiazide diuretic, alpha blocker, beta blocker, or an angiotensin converting enzyme inhibitor) and angina (monotherapy or in combination with other anti-anginal medicinal products in patients with angina that is refractory to nitrates and/or to adequate doses of beta blockers), the initial dose is 5 mg amlodipine once daily which may be increased to a maximum dose of 10 mg depending on the individual patient’s response.
• Children with hypertension from 6 – 17 years of age: The starting dose is 2.5 mg once daily (using other suitable preparation), up-titrated to 5 mg once daily if blood pressure goal is not achieved after 4 weeks.
• Elderly: Increase of the dosage should take place with care.
• Hepatic impairment: Start at the lower end of the dosing range. Amlodipine should be titrated slowly and monitor closely in patients with severe hepatic impairment.

Usage:

Drug is orally administered.

• Known hypersensitive to any of the active substance or excipients of the product.
• Severe hypotension.
• Shock (including cardiogenic shock).
• Obstruction of the outflow tract of the left ventricle (e.g. high grade aortic stenosis).
• Haemodynamically unstable heart failure after acute myocardial Infarction.

• Somnolence, dizziness, headache (especially at the beginning of the treatment).
• Palpitations
• Flushing
• Abdominal pain, nausea.
• Ankle swelling.
• Oedema, fatigue.

• Patients with heart failure should be treated with caution.
• Use in pregnancy is only recommended when there is no safer alternative and when the disease itself carries greater risk for the mother and foetus. A decision on whether to discontinue breast-feeding or to discontinue therapy with amlodipine should be made taking into account the benefit of breast-feeding to the child and the benefit of amlodipine therapy to the mother.
• Patients should be aware of how they react to drug before driving or operating machinery.